Requested Daily News Article

Decoying AGEs (Wednesday October 18 2006) An interesting idea in a review paper from earlier this year: "The receptor for advanced glycation end products (RAGE) is a cell-bound receptor of the immunoglobulin superfamily which may be activated by a variety of [advanced glycation end products or AGEs] ... soluble RAGE (sRAGE) [lacks] the transmembrane domain and therefore circulates in plasma. By competing with cell-surface RAGE for ligand binding, sRAGE may contribute to the removal/neutralization of circulating ligands thus functioning as a decoy. Clinical studies have recently shown that higher plasma levels of sRAGE are associated with a reduced risk of coronary artery disease, hypertension, the metabolic syndrome, arthritis and Alzheimer's disease." If AGEs are binding to sRAGE instead of damaging your cells, this might just be a good thing - but not as good as getting rid of the AGEs in the first place. Link to original article   Share |

Prior News Study: DHEA Doesn't Work A Reminder of the Trend On Stem Cells Versus Parkinson's Perspectives on a Decade of Research Stem Cells Versus Nerve Damage

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