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Stem Cells Versus Corneal Damage
(Friday April 10 2009)
 | From EurekAlert!: "Stem cells collected from human corneas restore transparency and don't trigger a rejection response when injected into eyes that are scarred and hazy ... The findings suggest that cell-based therapies might be an effective way to treat human corneal blindness and vision impairment due to the scarring that occurs after infection, trauma and other common eye problems ... corneal stem cells were able to remodel scar-like tissue back to normal. ... Our experiments indicate that after stem cell treatment, mouse eyes that initially had corneal defects looked no different than mouse eyes that had never been damaged ... The ability to grow millions of the cells in the lab could make it possible to create an off-the-shelf product, which would be especially useful in countries that have limited medical and surgical resources but a great burden of eye disease due to infections and trauma. ... The cornea and [its] stem cells themselves appear to be 'immune privileged,' meaning they don't trigger a significant immune response even when transplanted across species." |
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